Professor Karen Barlow, MBChB, Ph.D., MSc, RACP, Chair in Paediatric Rehabilitation, Child Health Research Centre, Faculty of Medicine, The University of Queensland, Australia
This is a summary of the curriculum vitae (CV) of Professor Karen Maria Barlow, MBChB, Ph.D., MSc, RACP, Chair in Paediatric Rehabilitation, Child Health Research Centre, Faculty of Medicine, The University of Queensland, Australia.
Professor Barlow is a paediatrician who specializes in neurotrauma like concussions and post-concussion syndrome. She is the Director of the KidStim Lab, which investigates the use of non-invasive brain stimulation techniques to improve outcomes in children with neurological impairment, at the Child Health Research Centre of the University of Queensland.
She published >100 articles that have been cited 8870 times (Google Scholar), and which include high-impact journals like The Lancet (Barlow and Minns 2000), The Lancet Neurology (Maas et al. 2017; 2022; Stewart et al. 2019), JAMA (Grool et al. 2016; Zemek et al. 2016), JAMA Neurology (Giza et al. 2018 [last author]), JAMA Pediatrics (Ledoux et al. 2019), JAMA network open (Vaughan et al. 2023), The British journal of sports medicine (Schneider et al. 2014; 2018; Taylor et al. 2014; Yeates et al. 2023), Pediatrics (Barlow et al. 2005; 2010; 2020; Davis et al. 2024), and Brain Stimulation (Seeger et al. 2017 [last author]; Zewdie et al. 2020).
Her research interests are:
- Paediatric Neurology
- Neurotrauma
- Concussion and mild traumatic brain injury
- Headache and pain disorders
- Clinical trials
According to her own description:
“I am an academic paediatric neurologist, clinical researcher, and specialist in acquired brain injury in children and adolescence. I studied at the University of Edinburgh and British Columbia before taking up my first academic position at the University of Calgary in 2002. Here I developed and directed the Traumatic Brain Injury and Concussion Research Program at the Alberta Children’s Hospital and where I cemented my interest in the biology and treatment of children with brain injuries. I have extensive clinical research experience, devising and overseeing clinical trials in children both nationally and internationally. I moved to the Child Health Research Centre at the University of Queensland, Australia in October 2017 and joined the Queensland Paediatric Rehabilitation Service and Queensland Cerebral Palsy Rehabililation Centre to facilitate research into improving the health outcomes of children with acquired brain injury in Queensland and Australia.
My research focuses on the neurobiological signatures and treatment of subtle neurological dysfunction in mild traumatic brain injury and concussion, especially the behavioural and cognitive impairments that are found in post-concussion syndrome. I use multimodal neurological assessments to do this. My research explores combining neuroimaging and neurophysiological investigations, including perfusion studies using MRI (ASL-fMRI) and transcranial magnetic stimulation to help us understand the changes in the brain in children who are slow to recovery following a concussion. This is to help us develop and assess more effective and tailored treatments for children with concussion and traumatic brain injury. I explore novel therapies for children with persistent post-concussive symptoms in clinical trials including the use of neuraceuticals, pharmacotherapies, and non-invasive brain stimulation treatment.
I am the director of the newly-established KidStim Lab at the Child Health Research Centre. This is the first non-invasive neuromodulation facility aimed at improving the health outcomes of children with brain injury in Australia and is led by a mulitdisciplinary team of clinicians and scientists from Brisbane bring a unique clinical and scientific knowledge-base to help achieve our goals. Rehabilitation therapy in combination with repetitive transcranial direct current stimulation (rTMS) and other direct current stimulation modalities (e.g. tDCS) will be explored. It also offers the potential for treatment of the mood and behavioural disorders (e.g. depression and anxiety) commonly seen after brain injury but also so disruptive to the life of the normally developing teenager.”
It will be a pleasure and honor to hear her explain about concussion and post-concussion syndrome to our audience at Fujita Health University.
CURRICULUM VITAE
EDUCATION
Degrees
2017-2020 Doctor of Philosophy (Medicine: Neuroscience), The University of Queensland
2013-2015 Master of Science, Clinical Trials, London School of Hygiene and Tropical Medicine, University of London
1993-2002 Certificate of Completion of Specialized Training, Pediatric Neurology,
General Medical Council (UK)
1993-1996 Certificate, Member of Royal College of Pediatrics and Community Child Health
1991-1993 Certificate, Member of Royal College of Physicians (UK)
1984-1989 Bachelor of Medicine, Bachelor of Surgery (MBChB), University of Edinburgh
Credentials
2021 GAICD, Member of the Australian Institute of Company Directors, Company Director Course Award
2017 Fellow and Specialist in Pediatric Neurology, Royal Australasian College of Physicians
2002 Specialist in Pediatric Neurology, Alberta College of Physicians and Surgeons
2001 License of Medical College of Canada
2000 Specialist in Paediatric Neurology, Royal College of Pediatrics and Child Health
1990 General Medical License, General Medical College, UK
EMPLOYMENT
Current
2021- Professor, Faculty of Medicine, The University of Queensland
2017- Dr. Paul Hopkins Chair of Paediatric Rehabilitation
Conjoint position: University of Queensland and Children’s Health Queensland
2017- Attending Consultant Paediatric Neurologist
Children’s Health Queensland Hospital and Health Services(CHQ)
2017- Adjunct Associate Professor of Clinical Neurosciences and Paediatrics,
University of Calgary
Previous
2017-2020 Associate Professor, Paediatric Neurology, Faculty of Medicine
University of Queensland
2011-2017 Associate Professor of Clinical Neurosciences and Pediatrics
University of Calgary
2009-2010 Division Chief, Paediatric Neurology, Alberta Children’s Hospital
2002-2017 Attending Consultant Paediatric Neurologist
Alberta Children’s Hospital
2003-2011 Assistant Professor of Clinical Neurosciences and Pediatrics,
The University of Calgary
2002-2003 Clinical Assistant Professor, Pediatric Neurology
The University of Calgary, Alberta Children’s Hospital
2000-2002 Neurology Fellow
Pediatrics, Medicine/BC Children’s Hospital, University of British Columbia
1999-2000 Senior Specialist Registrar
Royal Hospital for Sick children, Edinburgh. Post-graduate: Pediatric Neurology
1997-1999 Research Fellow
United Kingdom, Medicine/Royal Children’s Hospital, University of Edinburgh
1996-1997 Neurology Fellow
Pediatrics, Medicine/BC Children’s Hospital, University of British Columbia
1993-1996 Specialist Registrar
Pediatric Neurology, Southeast Scotland Training Program
1990-1993 Senior house office (Senior resident)
General Pediatrics, Royal Hospital for Sick Children
1989-1990 House officer (Junior resident)
Medicine, Roodlands General Hospital ; Surgery, Kirkcaldy General Hospital
RECOGNITIONS/AWARDS
2018 Fellow, Royal Australasian College of Physicians (Paediatric Neurology)
2017 Section of Paediatric Neurology Service Award,
Alberta Children’s Hospital
2017 Department of Paediatrics Clinician of the Year Award,
University of Calgary
2015 Mentorship award, Depart of Pediatrics, University of Calgary
2014 Nelson Butters Award for Best Original Research Article 2013,
National Academy of Neuropsychology
2013 Hellbender Honor Roll, Recognition of invaluable contribution to medical education
University of Calgary
2011 Robert Haslam Teaching Award, Distinction
Paediatric Neurology Residency Program
2006 Program Distinction – Letter of Excellence in Teaching,
University of Calgary
2006 Member, Helfer Society – Significant contribution researching child abuse
ADMINISTRATIVE RESPONSIBILITIES
Faculty
2021 – 2022 Interim Director, UQ Child Health Research Centre
2020 – Faculty of Medicine International Committee Member, UQ
2017 – 2021 Executive Committee, Child Health Research Centre, UQ
2015 – 2017 Research institute, Event organizer, ACHRI Annual Summer Student Research Symposium, University of Calgary
2005 – 2011 Research Institute Co-chair: Behaviour and Developing Brain Theme of Alberta Children’s Hospital Research Institute for Maternal and Child Health, University of Calgary
2010 – 2012 Committee, Member or participant, Robert Haslam Chair Committee
2009 – 2012 Training program, CIHR/ACHRI Training Program Finance Committee
University
2016 – 2017 Behaviour and the Developing Brain Theme Committee member, Alberta Children’s Hospital Research Institute, University of Calgary
2015 – 2017 Integrated Concussion Research Program Steering Committee, University of Calgary
Regional
2020 – Member, Research Council, Children’s Hospital Queensland
2020 – Chair, Research Working Group, Queensland Paediatric Rehabilitation Service
2015 – 2017 Committee Member, Concussion Care Pathway: Child and Youth Strategic Clinical Network, Alberta Health Services
2015 – 2017 Community engagement: Event organizer, Curious about Concussions: An education session for children and families with concussion. Organisers Karen Barlow and Keith Yeates
2011 – 2012 Committee Member, Southern Alberta Ambulatory Care Evaluation Project Phase II, Alberta Children’s Hospital, Alberta Health Services
2010 – 2011 Program, Divisional director, Ambulatory Care Evaluation Project, Alberta Children’s Hospital, Alberta Health Services
2008 – 2010 Program Lead, Division of Pediatric Neurology, Alberta Children’s Hospital
2002 – 2017 Program development, Director, Brain Injury and Rehabilitation Program at the Alberta Children’s Hospital
National/International Health
2022 – Online TBI Education Course Development, International Child Neurology Society Association
2021 – Vice President, Australian Brain Stimulation Society
2021 – Paediatric Steering Committee, International Headache Society
Nov 2021 MRFF Rare Diseases and Unmet Medical Need: Grant Assessment Committee
2021-2021 NHMRC MRFF 2020 International Clinical Trial Collaborations: Round 2 Grant Assessment Committee
2015 – 2015 Tenure or promotion review/FEC, Reviewer, University of British Columbia Department of Physical Therapy Promotion and Tenure Committee: Dr. Virji-Babul
2015 – 2015 External reviewer, Canada Research Chairs – expert reviewer
2014 – 2015 External review, Advisor, Ontario Brain Institute (OBI) and the Institute for Clinical Evaluative Sciences (ICES)
2014 – 2014 External reviewer, South African Medical Research Council external reviewer grant application on concussion and TBI
2014 – 2015 Conference organization, Director, Child Neurology Subspecialty in Focus: C83: Concussion Assessment and Management in the Youth Athlete
2014 – 2017 Training program, Reviewer, Trainee Travel Award Competition- Canada Pediatric mTBI Common Data Study (CIHR)
2014 – 2017 Committee Member, Canadian Stroke Best Practice Recommendations advisory committee for pediatric stroke rehabilitation.
2013 – 2017 Advisory board Member, International collaboration in Traumatic Brain Injury (CIHR)
2013 – 2014 Advisory board Member, Ontario Neurotrauma Foundation, Advisory Board for Treatment of Post-Concussion Syndrome in Children
2012 – 2012 Advisory Committee Member, CIHR, Advisory meeting, New Opportunities in Traumatic Brain Injury
RESEARCH PUBLICATIONS
1. Stein A, Thorstensen JR, Ho JM, Ashley DP, Iyer KK, Barlow KM. Attention Please! Unravelling the link between brain network connectivity and cognitive attention following acquired brain injury: A systematic review of structural and functional measures. Brain connectivity. 2023 Nov 29(ja).
2. Stein A, Vinh To X, Nasrallah FA, Barlow KM. Evidence of ongoing cerebral microstructural reorganization in children with persisting symptoms following mild traumatic brain injury: a NODDI DTI analysis. Journal of Neurotrauma. 2023 Nov 29.
3. Davis GA, Schneider KJ, Anderson V, Babl FE, Barlow KM, Blauwet CA, Bressan S, Broglio SP, Emery CA, Echemendia RJ, Gagnon I. Pediatric sport-related concussion: recommendations from the Amsterdam Consensus Statement 2023. Pediatrics. 2024 Jan 1;153(1).
4. Bagg, Matthew, Hellewell, Sarah Claire, Keeves, Jemma, Antonic-Baker, Ana, McKimmie, Ancelin, Hicks, Amelia, Gadowski, Adelle, Newcombe, Virginia, Barlow, Karen Maria, Balogh, Zsolt, Ross, Jason, Law, Meng, Caeyenberghs, Karen, Parizel, Paul, Thorne, Jacinta, Papini, Melissa, Gill, Geena, Jefferson, Amanada, Ponsford, Jennie, Lannin, Natasha A, O’Brien, Terence J., Cameron, Peter, Cooper, D. James, Rushworth, Nick, Gabbe, Belinda, and Fitzgerald, Melinda (2023). The Australian Traumatic Brain Injury Initiative: systematic review of predictive value of biological markers for people with moderate-severe traumatic brain injury. Journal of Neurotrauma 0 (ja) . https://doi.org/10.1089/neu.2023.0464
5. Maas AI, Menon DK, Manley GT, Abrams M, Åkerlund C, Andelic N, Aries M, Bashford T, Bell MJ, Bodien YG, Brett BL. et al. Traumatic brain injury: progress and challenges in prevention, clinical care, and research. The Lancet Neurology. 2022 Nov 1;21(11):1004-60.
6. Stein A, Barlow K. Home based remotely supervised tDCS in children with acquired brain injury: a feasibility study protocol. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation. 2023 Jan 1;16(1):300.
7. Banoei MM, Lee CH, Hutchison J, Panenka W, Wellington C, Wishart DS, Winston BW. et al. Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months. Critical Care. 2023 Jul 22;27(1):295.
8. Craig BT, Geeraert B, Kinney‐Lang E, Hilderley AJ, Yeates KO, Kirton A, Noel M, MacMaster FP, Bray S, Barlow KM, Brooks BL. Structural brain network lateralization across childhood and adolescence. Human Brain Mapping. 2023 Mar;44(4):1711-24.
9. Yeates, KO Barlow KM Health care impact of implementing a clinical pathway for acute care of pediatric concussion: A stepped wedge, cluster randomised trial Accepted 14/5//2023 Canadian Journal of Emergency Medicine
10. Barlow KM, Post-traumatic headache: An unmet medical need Headache 61(10):1465-66
11. Enticott, P. G., Barlow, K., Guastella, A. J., Licari, M. K., Rogasch, N. C., Middeldorp, C. M., Clark, S. R., Vallence, A., Boulton, K. A., Hickie, I. B., Whitehouse, A. J. O., Galletly, C., Alvares, G., Fujiyama, H., Heussler, H., Craig, J., Kirkovski, M., Mills, N. T., Rinehart, N. J., Donaldson, P. H., Ford, T. C., Caeyenberghs, K., Albein-Urios, N., Bekkali, S., & Fitzgerald, P. B. Repetitive transcranial magnetic stimulation (rTMS) in autism spectrum disorder: protocol for a multicentre randomised controlled clinical trial. BMJ Open 2021;0:e046830. doi:10.1136/bmjopen-2020-046830
12. Stein A, Iyer KK, Khetani AM, Barlow KM. Changes in working memory-related cortical responses following pediatric mild traumatic brain injury: A longitudinal fMRI study Journal of Concussion 4 April 2021. http://doi:10.1177/20597002211006541
13. Karen Maria Barlow, Kartik Iyer, Tingting Yan, Alex Scurfield, Helen L. Carlson, Yang Wang (2021) Cerebral blood flow predicts recovery in children with persistent post-concussion symptoms following mild traumatic brain injury Journal of Neurotrauma. 38 (16): 2275-83 http://doi.org/10.1089/neu.2020.7566
14. Franz E Babl, Emma Tavender, Dustin W Ballard, Meredith L Borland, Ed Oakley, Elizabeth Cotterell, Lambros Halkidis, Stacy Goergen, Gavin A Davis, David Perry, Vicki Anderson, Karen M Barlow, Peter Barnett, Scott Bennetts, Roisin Bhamjee, Joanne Cole, John Craven, Libby Haskell, Ben Lawton, Anna Lithgow, Glenda Mullen, Sharon O’brien, Michelle Paproth, Catherine L Wilson, Jenny Ring, Agnes Wilson, Grace Sy Leo, Stuart R Dalziel Paediatric Research in Emergency Departments International Collaborative (PREDICT) (2021) Australian and New Zealand guideline for mild to moderate head injuries in children Emergency Medicine Australasia 33(2): 214-31
15. Z Ofoghi, CS Rohr, D Dewey, S Bray, KO Yeates, M Noel, KM Barlow Functional connectivity of the anterior cingulate cortex with pain-related regions in children with post-traumatic headache Cephalalgia Reports 4, 25158163211009477
16. Anh Ly, Roger Zemek, Bruce Wright, Jennifer Zwicker, Kathryn Schneider, Angelo Mikrogianakis, Alf Conradi, David Johnson, Brenda Clark, Karen Barlow, Joseph Burey, Ashley Kolstad, Keith Yeates (2021) “What is the actual goal of the pathway?” Examining emergency department clinicians’ perspectives of the implementation of a pediatric concussion pathway using the Theoretical Domains Framework. BMC Health Services Research 21(1):119 doi: 10.1186/s12913-021-06110-2
17. Schneider KJ, Meeuwisse WH, Barlow KM, Emery, CA. (2021). Cervico-vestibular rehabilitation following sport-related concussion: A follow-up study. British Journal of Sports Medicine. 52(2): 100-101.
18. Schneider, K.J., Nettel-Aguirre, A., Palacios-Derflingher, L., Mrazik, M., Brooks, B.L., Woollings, K., Blake, T., McKay, C., Lebrun, C., Barlow, K., Taylor, K., Lemke, N., Meeuwisse, W.H., Emery, C.A. (2021) Concussion Burden, Recovery, and Risk Factors in Elite Youth Ice Hockey Players Clinical journal of sport medicine 31(1):70-77 1 January 2021
19. Barlow KM, Brooks BL, Esser MJ, Kirton A, Mikrogianakis A, Zemek RL, MacMaster FP, Nettel-Aguirre A, Yeates KO, Kirk V, Hutchison JS, Crawford S, Turley B, Cameron C, Hill MD, Samuel T, Buchhalter J, Richer L, Platt R, Boyd R, Dewey D. (2020). Efficacy of Melatonin for sleep disturbance in Children with Postconcussive Symptoms: secondary analysis of a Randomized Clinical Trial. J Neurotrauma. 38(8):950-959 https://doi.org/10.1089/neu.2020.7154
20. Iyer, K.K., Zalesky, A., Cocchi, L. and Barlow, K.M. (2020). Neural Correlates of Sleep Recovery following Melatonin Treatment for Pediatric Concussion: A Randomized Controlled Trial. J Neurotrauma (2020) 37(24):2647-55. doi: 10.1089/neu.2020.7200
21. Zewdie, E., Ciechanski, P., Kuo, H.C., Giuffre, A., Kahl, C., King, R., Cole, L., Godfrey, H., Seeger, T., Swansburg, R., Damji, O., Rajapakse, T., Hodge, J., Nelson, S., Selby, B., Gan, L., Jadavji, Z., Larson, J.R., MacMaster, F., Yang, J.F., Barlow, K., Gorassini, M., Brunton, K. and Kirton, A. (2020). Safety and tolerability of transcranial magnetic and direct current stimulation in children: Prospective single center evidence from 3.5 million stimulations. Brain Stimul 13, 565-575.
22. Ofoghi, Z., Dewey, D. and Barlow, K.M. (2020). A Systematic Review of Structural and Functional Imaging Correlates of Headache or Pain after Mild Traumatic Brain Injury. J Neurotrauma 37, 907-923.
23. SF Huth, A Slater, M Waak, K Barlow, S Raman Predicting Neurological Recovery after Traumatic Brain Injury in Children: A Systematic Review of Prognostic Models Journal of neurotrauma 37 (2020), 2141-2149
24. MacMaster, F.P., McLellan, Q., Harris, A.D., Virani, S., Barlow, K.M., Langevin, L.M., Yeates, K.O. and Brooks, B.L. (2020). N-Acetyl-Aspartate in the Dorsolateral Prefrontal Cortex Long After Concussion in Youth. J Head Trauma Rehabil 35, E127-E135.
25. Joanne M George, Alex M Pagnozzi, Samudragupta Bora, Roslyn N Boyd, Paul B Colditz, Stephen E Rose, Robert S Ware, Kerstin Pannek, Jane E Bursle, Jurgen Fripp, Karen Barlow, Kartik Iyer, Shaneen J Leishman, Rebecca L Jendra. (2020). Prediction of childhood brain outcomes in infants born preterm using neonatal MRI and concurrent clinical biomarkers (PREBO-6): study protocol for a prospective cohort study. BMJ Open. 10(5) e036480
26. Barlow KM, Brooks, B. L., Esser, M. J., Kirton, A., Mikrogianakis, A., Zemek, R. L, MacMaster, F. P., Nettel-Aguirre, A.,Yeates, K. O.Kirk, V.Hutchison, J. S.Crawford, S.Turley, B.Cameron, C.Hill, M. D.Samuel, T.Buchhalter, J.Richer, L. Platt, R.Boyd, R.Dewey, D. Efficacy of Melatonin in Children with Post-Concussive Symptoms: A Randomized Clinical Trial Pediatrics Pediatrics 2020, 145(4).
27. Brooks, Brian L; Virani, Shane; Khetani, Aneesh; Carlson, Helen; Jadavji, Zeanna; Mauthner, Micaela; Low, Trevor; Plourde, Vickie; MacMaster, Frank; Bray, Signe; Harris, Ashley; Lebel, Catherine; Lebel, Marc; Esser, Michael; Yeates, Keith O; Barlow, Karen Functional magnetic resonance imaging study of working memory several years after pediatric concussion Brain Inj (2020),May 34(7):895-904
28. MacMaster, F.P., McLellan, Q., Harris, A.D., Virani, S., Barlow, K.M., Langevin, L.M., Yeates, K.O. and Brooks, B.L. (2020). N-Acetyl-Aspartate in the Dorsolateral Prefrontal Cortex Long After Concussion in Youth. J Head Trauma Rehabil 35 (2):E127-E135.
29. Zewdie E., Ciechanski P., Kuo H., Giuffre A., Kahl C., King R., Cole L., Godfrey H., Seeger T., Swansburg R., Damji O., Rajapakse T., Hodge J., Nelson S., Selby B., Gan L., Jadavji Z., Larson J., MacMaster F., Yang J., Barlow K., Gorassini M., Brunton K., Kirton A. Safety and tolerability of transcranial magnetic and direct current stimulation in children: Prospective single center evidence from 3.5 million stimulations. Brain Stimulation (2019) 13(3):565-575.
30. Barlow KM, Girgulis KA ; Goldstein G, Crowe EG, Vo MK, Su P, Esser MJ, Dewey DM, Kirk VG, Sleep parameters and overnight urinary melatonin production in children with persistent post-concussion symptoms Pediatric Neurology 2019 105:27-34 doi:10.1016/j.pediatrneurol.2019.11.006 (Epub 17 Dec 2019)
31. Iyer KK, Zalesky A, Barlow KM,Cocchi L. Default mode network anatomy and function is linked to pediatric concussion recovery Annals of Clinical and Translational Neurology 2019 Dec; 6(12):2544-2554 (Epub 22 Nov 2019)
32. Iyer KK, Barlow KM, Brooks B, Ofoghi Z, Zalesky A, Cocchi L. Relating brain connectivity with persistent symptoms in pediatric concussion. Annals of Clin Trans Neurology. 2019 May 6(5):954-961
33. MacMaster FP, McLellan, Q, Harris A, Virani, S. Barlow KM Langevin LM Yeates KO, Brooks B (2020) N-Acetyl-Aspartate in the Dorsolateral Prefrontal Cortex Long After Concussion in Youth; J Head Trauma Rehab 35(2): E127-E135
34. Khetani, A; Rohr, C; Sojoudi, A; Bray, S; Barlow KM. Alteration in cerebral activation during a working memory task following pediatric mild traumatic brain injury: a prospective controlled cohort study J Neurotrauma (2019) Dec1;36(23):3274-3283 Epub Aug 9
35. King R, T Seeger, E Zewdie, P Ciechanski, O Damji, Kirton A, Barlow KM. Longitudinal assessment of cortical excitability in children with mild traumatic brain injury and persistent post-concussive symptoms. Frontiers Neurology 2019 May 17; 10:451. doi: 10.3389/fneur. 2019.00451.
36. King R, Grohs M, Kirton A, Lebel C, Barlow KM Microstructural neuroimaging of motor tracts in persistent post-concussion syndrome: A prospective controlled cohort study Neuroimage: clinical 2019;23:101842 Epub 2019 May6
37. Tomfohr L, Madsen J, Plourde, V., Virani, Shane; Barlow, Karen; Brooks, Brian L, Yeates, Keith O; A pilot randomized control trial of cognitive-behavioural therapy for insomnia in adolescents with persistent postconcussion symptoms (2020) J Head Trauma Rehabilitation 35(2):e103-112
38. Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O’Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH. (2019). Primum non nocere: a call for balance when reporting on CTE. Lancet Neurol. 2019;18(3):231-3
39. Yeates KO, Tang K, Barrowman NJ, Freedman SB, Gravel J, Gagnon I, Barlow KM et al. Derivation and initial validation of clinical phenotypes of children presenting with concussion acutely in the Emergency Department: Latent class analysis of a multicentre, prospective cohort, observational study J Neurotrauma. 2019;7(7):e017012
40. Brooks BL, Low TA, Plourde V, Virani S, Jadavji Z, MacMaster FP, Barlow KM, Yeates KO Cerebral blood flow in children and adolescents several years after concussion. Brain Inj. 2019;33(2):233-41
41. Barlow KM, Esser MJ, Veidt M, Boyd R Melatonin as a Treatment after Traumatic Brain Injury: A Systematic Review and Meta-Analysis of the Pre-Clinical and Clinical Literature J Neurotrauma 2019; 36(4): 523-537
42. Brooks BL, Plourde V, Beauchamp MH, Barlow KM et al. Predicting Psychological Distress after Pediatric Concussion. J Neurotrauma 2019; 36(5): 679-85
43. V Plourde, H Daya, TA Low, KM Barlow, BL Brooks (2019) Evaluating anxiety and depression symptoms in children and adolescents with prior mild traumatic brain injury: agreement between methods and respondents Child neuropsychology 25 (1), 44-59
44. Ledoux AA, Tang K, Yeates KO, Pusic MV, Boutis K, Craig WR, Barlow KM et al. Natural Progression of Symptom Change and Recovery From Concussion in a Pediatric Population. JAMA Pediatr. 2019;173(1):e183820
45. Meeryo Choe and Karen M Barlow. (2018). Pediatric Traumatic Brain Injury and Concussion (Invited Review Article). Continuum: American Academy of Neurology. 24(1, Child Neurology): 300-311
46. Giza, C; Meeryo, C. Barlow, KM, (2018). Determining if rest is best after concussion? JAMA neurology 75(4): 399-400.
47. Bresee N, Aglipay M, Dubrovsky AS, Ledoux A-A, Momoli F, Gravel J, Barlow KM et al. (2018). No association between metoclopramide treatment in ED and reduced risk of post-concussion headache. The American journal of emergency medicine. 2018;36(12):2225-31
48. Karen M. Barlow. (2018). Guest Editorial: Canadian Guideline on Sport Concussion Guidelines. The Chronicle of Neurology & Psychiatry.
49. Yeates, K. O., Beauchamp, M., Craig, W., Doan, Q., Zemek, R., Bjornson, B. B., Gravel, G., Mikrogianakis, A., Goodyear, B., Abdeen, N., Beaulieu, C., Dehaes, M., Deschenes, S., Harris, A., Lebel, C., Lamont, R., Williamson, T., Barlow, K. M., Bernier, F., Brooks, B. L., Emery, C., Freedman, S. B., Kowalski, K., Mrklas, K., Tomfohr-Madsen, L., & Schneider, K., on behalf of Pediatric Emergency Research Canada (2017). (2017). The Advancing Concussion Assessment in Pediatrics (A-CAP) study: Protocol for a prospective, concurrent cohort longitudinal study of mild traumatic brain injury in children. British Medical Journal Open. 7(e017012). http://dx.doi.org/10.1136/bmjopen-2017-017012
50. Yamakawa GR, Salberg S, Barlow KM, Brooks BL, Esser MJ, Yeates KO, Mychasiuk R. (2017). Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology, gene expression, and response to melatonin treatment in rats. Exp Neurol. 295(Sep): 55-65. http://dx.doi.org/doi: 10.1016/j.expneurol.2017.06.001.
51. Seeger TA, Kirton A, Esser MJ, Gallagher C, Dunn J, Zewdie E, Damji O, Ciechanski P, Barlow KM Cortical excitability after pediatric mild traumatic brain injury. Brain Stimul. 2017 Mar-Apr;10(2):305-314. doi: 10.1016/j.brs.2016.11.011. Epub 2016 Nov 19.
52. Aynur Ozge; Ishaq Abu Arafeh; Amy A Gelfand; Peter James Goadsby; Jean Christophe Cuvellier; Massimiliano Valeriani; Alexey Sergeev; Karen Barlow; Derya Uludüz; Osman Özgür Yalın; Noemi Faedda; Richard B Lipton; Alan Rapoport; Vincenzo Guidetti. (2017). Experts’ opinion about the Pediatric Secondary Headaches Diagnostic Criteria of the ICHD-3 beta. The Journal of Headache and Pain. 18(113).
53. Aynur Ozge; Ishaq Abu Arafeh; Amy A Gelfand; Peter James Goadsby; Jean Christophe Cuvellier; Massimiliano Valeriani; Alexey Sergeev; Karen Barlow; Derya Uludüz; Osman Özgür Yalın; Noemi Faedda; Richard B Lipton; Alan Rapoport; Vincenzo Guidetti. (2017). Experts’ opinion about the Primary Headaches Diagnostic Criteria of the ICHD-3 beta in children and adolescents. The Journal of Headache and Pain. 18(109).
54. McChesney-Corbeil J, Barlow K, Quan H, Chen G, Wiebe S, Jette N. (2017). Validation of a Case Definition for Pediatric Brain Injury Using Administrative Data. Can J Neurol Sci.44(2): 161-9.
55. Andrew I R Maas, David K Menon, P David Adelson, Nada Andelic, Michael J Bell, Antonio Belli, Peter Bragge, A Brazinova, András Büki, Randall M Chesnut, Giuseppe Citerio, Mark Coburn, D Jamie Cooper, A Tamara Crowder, Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A van Essen, Valery L Feigin, Guoyi Gao, Joseph Giacino, Laura E Gonzalez-Lara, Russell L Gruen, Deepak Gupta, Jed A Hartings, Sean Hill, Ji-yao Jiang, Naomi Ketharanathan, Erwin J O Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Barlow KM …for the InTBIR Participants and Investigators. (2017). Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. The Lancet Neurology. 16(12).
56. KM Barlow, LD Marcil, D Dewey, H Carlson, FP MacMaster, BL Brooks, and RM Lebel. (2016). Cerebral perfusion and its relationship to post-concussion syndrome in mild traumatic brain injury: a prospective controlled cohort study. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 43(S2): S7.
57. Hebert D, Lindsay MP, McIntyre A, Kirton A, Rumney PG, Bagg S, et al. Canadian stroke best practice recommendations: Stroke rehabilitation practice guidelines, update 2015. International Journal of Stroke. 2016;11(4):459-84.
58. Aneesh Khetani, Angelo Mikrogianakis, Brenda Turley, Karen M. Barlow. (2016). Incorporating a computerized cognitive battery into the emergency department care of paediatric mild traumatic brain injuries- is it feasible?. Pediatric Emergency Care. Dec: 1-6.
59. Brian Brooks, Hussain Daya, Annie Khan, Helen Carlson, Angelo Mikrogianakis, Karen M. Barlow. (2016). Cognition in the emergency department as a predictor of recovery after pediatric mild traumatic brain injury. Journal of the International Neuropsychological Society. 22(4): 379-87.
60. KM Barlow, LD Marcil, D Dewey, H Carlson, FP MacMaster, BL Brooks, and RM Lebel. (2016). Cerebral Perfusion changes in Post-Concussion Syndrome: A prospective controlled cohort study. J Neurotrauma. (23 Aug). 1: 1-6.
61. Brian Brooks; Angelo Mikrogianakis; Hussain Daya; Trevor Low; Annie Khan; Karen M Barlow. (2016). Test or rest? Computerized cognitive testing after pediatric mild traumatic brain injury does not delay recovery. J Neurotrauma. : 1-6. http://dx.doi.org/10.1089/neu.2015.4301.
62. Barlow KM. (2016). Post-concussion syndrome: A review. Journal of Child Neurology. 31(1): 57-6.
63. Roger Zemek; Nick Barrowman; Stephen B. Freedman, Jocelyn Gravel; Isabelle Gagnon; Candice McGahern; Mary Aglipay; Gurinder Sangha; Kathy Boutis; Darcy Beer; William Craig; Emma Burns; Ken J. Farion; Angelo Mikrogianakis; Karen Barlow; Alexander S. Dubrovsky; Willem Meeuwisse; Gerard Gioia; William P. Meehan III; Miriam H. Beauchamp; Yael Kamil; Anne M. Grool; Blaine Hoshizaki, ; Peter Anderson; Brian L. Brooks; Keith Owen Yeates; Michael Vassilyadi; Terry Klassen; Michelle Keightley; Lawrence Richer; Carol DeMatteo; Martin H. Osmond. (2016). Clinical Risk Score for Persistent Post- Concussion Symptoms in Pediatrics. JAMA. 315(10): 1014-1025.
64. Grool AM, Aglipay M, Momoli F, Meehan WP, Freedman SB, Yeates KO, Barlow KM… Zemek, R. (2016). Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Post-concussive Symptoms in Children and Adolescents. PubMed PMID: 27997652. JAMA. 316(23): 2504-14.
65. Carolyn A Emery, Karen M. Barlow, Brian L. Brooks, Jeffrey E. Max, Angela Villavicencio-Requis, Vithya Gnanakumar, Helen Lee Robertson, Kathryn Schneider, Keith Owen Yeates. (2016). A systematic review of psychiatric, psychological, and behavioural outcomes following mild traumatic brain injury in children and adolescents. Canadian Journal of Psychiatry. 61(5): 259-69.
66. Urban KJ, Barlow K, Goodyear BG, Jimenez JJ, Dunn JF. (2015). Functional Near-Infrared Spectroscopy Reveals Reduced Inter-hemispheric Cortical Communication Following Pediatric Concussion. J Neurotrauma.32(11): 833-40.
67. Khetani A, Brooks BL, Mikrogianakis A, Barlow KM. (2015). Computerized cognitive assessment in the pediatric emergency room – is it feasible. Pediatric Emergency care. 32: 1-5.
68. Seeger T, Rajapaske T, Bodell L, Orr S, Lockyer L, Barlow KM. (2015). Occipital nerve blockade in the treatment of posttraumatic headaches. J of Child Neurology. 30(9): 1142-6. http://dx.doi.org/10.1177/0883073814553973.
69. Lindsay Jennifer May, Kelly Millar, Karen M Barlow, Frank Dicke. (2015). QTc Prolongation in Acute Pediatric Migraine. Pediatric Emergency Care. 31(6): 409-411. http://dx.doi.org/10.1097/PEC.0000000000000250.
70. Karen M. Barlow, Susan Crawford, Brian L. Brooks, Brenda Turley, Angelo Mikrogianakis. (2015). The incidence of Post-Concussion Syndrome remains stable following mild Traumatic Brain Injury in children. Pediatric Neurology. 53(6): 491-7.
71. Barlow KM, Brooks B, MacMaster F, Kirton A, Seeger T, Esser M, Crawford S, Nettel-Aguirre A, Zemek R, Mikrogianakis A, Kirk V, Emery CA, Johnson D, Hill MD, Buchhalter J, Turley B, Dewey D. (2014). A double-blinded, randomized placebo-controlled intervention trial of 3mg and 10mg sublingual Melatonin for Post-Concussion Syndrome in Youth (PlayGame Trial). Trials. 15(1): 271.
72. Kathryn J. Schneider, Willem H. Meeuwisse, Alberto Nettel-Aguirre, Karen Barlow, Lara Boyd, Jian Kang, Carolyn A. Emery. (2014). Cervico-vestibular rehabilitation in sport-related concussion: A Randomized Controlled Trial. British Journal of Sports Medicine. 48(17): 1294-8.
73. Smyth K, Sandhu SS, Crawford S, Dewey D, Parboosingh J, Barlow KM. (2014). The role of serotonin receptor alleles and environmental stressors in the development of post-concussive symptoms after pediatric mild traumatic brain injury. Developmental medicine and child neurology. 56(1): 73-7.
74. Brooks, B.L., Kadoura, B., Turley, B., Mikrogianakis, A., Barlow, K.M. (2014). Neurocognition in the emergency department following a mild traumatic brain injury in youth. J Neurotrauma. 31(20): 1744-9.
75. Brooks BL, Mrazik M, Barlow KM, McKay CD, Meeuwisse WH, Emery CA. (2014). Absence of Differences Between Male and Female Adolescents With Prior Sport Concussion. The Journal of head trauma rehabilitation. 29(3): 257-64.
76. Pringsheim T, Lam D, Day L, Genge A, Hogan DB, Shevell M, Fortin CM, Maxwell C, Fiebelkorn G, Barlow K, Kapral MK, Casha S, Mobach T, Johnston M, Jette N, Korngut L. (2013). Validation and interpretation of neurological registry data. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 40(4 Suppl 2).
77. Kuczynski A, Crawford S, Bodell L, Dewey D, Barlow KM. (2013). Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort. Dev Med Child Neurol. 26(6): 636-41.
78. Brooks BL, Kadoura B, Turley B, Crawford S, Mikrogianakis A, Barlow KM. (2013). Perception of Recovery After Pediatric Mild Traumatic Brain Injury Is Influenced by the “Good Old Days” Bias: Tangible Implications for Clinical Practice and Outcomes Research. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. 29(2): 186-93.
79. Brooks B, McKay C, Mrazik M, Barlow K, Meeuwisse W, Emery C. (2013). Subjective, but not objective, lingering effects of multiple past concussions in adolescents. J Neurotrauma. 2013(Apr).
80. Zemek R, Osmond MH, Barrowman N, et al. (2013). Predicting and preventing post-concussive problems in paediatrics (5P) study: protocol for a prospective multicentre clinical prediction rule derivation study in children with concussion. BMJ open. 3(8)e003550.
81. Jette N, Atwood K, Hamilton M, Hayward R, Day L, Mobach T, Maxwell C, Fortin CM, Fiebelkorn G, Barlow K, Shevell M, Kapral MK, Casha S, Johnston M, Wiebe S, Korngut L, Pringsheim T. (2013). Linkage between neurological registry data and administrative data. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 40(4 Suppl 2).
82. Hamilton M, Genge A, Johnston M, Lam D, Mobach T, Marriott J, Steeves T, Donner E, Wysocki J, Barlow K, Shevell M, Marrie RA, Casha S, Mackean G, Casselman L, Korngut L, Pringsheim T, Jette N. (2013). Patient recruitment by neurological registries. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 40(4 Suppl 2): S23-6.
83. Barlow K. (2012). Weight gain after childhood traumatic brain injury. Developmental medicine and child neurology. 54(7).
84. Sarnat HB, Wei XC, Flores-Sarnat L, Trevenen CL, Barlow K. (2012). Fetal opercular cavernous angioma causing cerebral cleft: contralateral primitive vascular anomaly and subicular dysgenesis. Journal of child neurology. 27(4).
85. Brooks BL, Barlow KM. (2011). A methodology for assessing treatment response in Hashimoto’s encephalopathy: a case study demonstrating repeated computerized neuropsychological testing. Journal of child neurology. 26(6).786-91.
86. B Brooks, T Fay, K Barlow. Hashimoto’s Encephalopathy: A Pediatric Case Study with Pre-and Post-Treatment Neuropsychological Testing Archives of Clinical Neuropsychology 25 (6), 475-583
87. Smith SE, Kirkham FJ, Deveber G, Millman G, Dirks PB, Wirrell E, Telfeian AE, Sykes K, Barlow K, Ichord R. (2011). Outcome following decompressive craniectomy for malignant middle cerebral artery infarction in children. Developmental medicine and child neurology. 53(1).
88. Barlow KM, Crawford S, Stevenson A, Sandhu SS, Belanger F, Dewey D. (2010). Epidemiology of post-concussion syndrome in pediatric mild traumatic brain injury. Pediatrics. 126(2): 374-81.
89. E Sherman, H Carlson, I Gaxiola-Valdez, X Wei, C Beaulieu, W Hader, B Brooks, A Kirton, K Barlow, M Hrabok, I Mohamed, S Wiebe Executive Functioning, DTI, and Cortical Thickness in Pediatric Epilepsy Archives of Clinical Neuropsychology 26 (6), 470-567
90. Barlow KM. (2007). Intracranial pressure measurement in children. Developmental medicine and child neurology. 49(12).
91. Glass HC, Boycott KM, Adams C, Barlow K, Scott JN, Chudley AE, Fujiwara TM, Morgan K, Wirrell E, McLeod DR. (2005). Autosomal recessive cerebellar hypoplasia in the Hutterite population. Developmental medicine and child neurology. 47(10). 691-5.
92. Soo I, Mah JK, Barlow K, Hamiwka L, Wirrell E. (2005). Use of complementary and alternative medical therapies in a pediatric neurology clinic. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 32(4). 524-8.
93. Wirrell E, Blackman M, Barlow K, Mah J, Hamiwka L. (2005). Sleep disturbances in children with epilepsy compared with their nearest-aged siblings. Developmental medicine and child neurology. 47(11)..
94. Barlow KM, Thomson E, Johnson D, Minns RA. (2005). Late neurologic and cognitive sequelae of inflicted traumatic brain injury in infancy. Pediatrics. 116(2). 174-185.
95. Wirrell E, Hill MD, Jadavji T, Kirton A, Barlow K. (2004). Stroke after varicella vaccination. The Journal of pediatrics. 145(6). 845-7.
96. Barlow K, Thompson E, Johnson D, Minns RA. (2004). The neurological outcome of non-accidental head injury. Pediatric rehabilitation. 7(3): 195-203.
97. Barlow KM, Minns RA. (2000). Annual incidence of shaken impact syndrome in young children. Lancet. 356(9241). 1571-1572
98. Barlow KM, Spowart JJ, Minns RA. (2000). Early post-traumatic seizures in non-accidental head injury: relation to outcome. Developmental medicine and child neurology. 42(9).591-4
99. Barlow KM, Gibson RJ, McPhillips M, Minns RA. (1999). Magnetic resonance imaging in acute non- accidental head injury. Acta paediatrica (Oslo, Norway : 1992). 88(7). 734-740
100. Barlow KM, Minns RA. (1999). The relation between intracranial pressure and outcome in non-accidental head injury. Developmental medicine and child neurology. 41(4). 220-5
101. Barlow KM, Milne S, Aitken K, Minns RA. (1998). A retrospective epidemiological analysis of non- accidental head injury in children in Scotland over a 15 year period. Scottish medical journal. 43(4). 112-4
102. Barlow KM, Mok JY. (1993). Dizygotic twins discordant for HIV and hepatitis C virus. Archives of disease in childhood. 68(4). 507.
103. Bonthron DT, Barlow KM, Burt AM, Barr DG. (1993). Parental consanguinity in the blepharophimosis, heart defect, hypothyroidism, mental retardation syndrome (Young-Simpson syndrome). Journal of medical genetics. 30(3). 225-256.
Book Chapters
1. Samuel TL, Barlow KM (2020) Paediatric Concussion, Diagnosis, Management and Rehabilitation. In: Tsao J. (eds) Traumatic Brain Injury (p 383-397) Springer, Cham https://doi.org/10.1007/978-3-030-22436-3_19
2. Non-accidental injury to children: A guide to management. In: Safeguarding and Protecting Children in the Early Years (2018) 2(5)1-18 Burton S, Reid J (Eds) Routledge
3. Barlow KM, Seeger TA. (2015). TMS neurophysiology of pediatric traumatic brain injury. Kirton A, Gilbert D. Pediatric Brain Stimulation: Mapping and Modulating the Developing Nervous System. Elsevier, United States.
4. Karen M. Barlow, Robert Forsyth, Robert A Minns. (2014). Accidental and Non-accidental Injuries by Physical and Toxic Agents. Robert Ouvrier, Jean Aicardi (eds) Aicardi’s Diseases of the Nervous System in Childhood. 4th. Mac Keith Press, London, UK
5. Karen M. Barlow. (2012). Traumatic Brain Injury including acute management. Oliver Dulac, Marysse Lassonde, Harvey B. Sarnat. Handbook of Clinical Neurology: Pediatric Neurology. 3(3): 891-9904. Published, Elsevier B.V., Netherlands.
6. Karen M Barlow. (2007). The neurorehabilitation of cerebral palsy. Harvey Sarnat, Paolo Curatolo. Handbook of Clinical Neurology: Malformations of the CNS. 1(87): 591-609. Published, Elsevier, Netherlands.
7. Karen M. Barlow, Robert A. Minns. (2005). Early post-traumatic seizures. Robert A. Minns and J. Keith Brown. Shaken Baby Syndrome and other Non-accidental Head injuries. 1(26). Published, Cambridge University Press, Cambridge, United Kingdom.
8. KM Barlow. (2005). Neurodevelopmental and neuropsychological outcome. Robert A Minns and Keith Brown. Shaken Baby Syndrome and Other Non-Accidental Head Injuries. 1(26). Published, Cambridge University Press, Cambridge, United Kingdom
